Manchester United will face Spanish side Real Sociedad in the Europa League last-16, while Tottenham have been drawn against Dutch club AZ Alkmaar. Scottish champions Rangers have been handed a tough clash with Fenerbahce, managed by Jose Mourinho.
If United progress, they will meet either Romania’s FCSB or French side Lyon in the quarter-finals. Spurs, or AZ Alkmaar, will face the winner of Ajax versus Eintracht Frankfurt, while Rangers will go up against either Roma or Athletic Bilbao if they advance past Fenerbahce.
With Manchester United and Tottenham on opposite sides of the draw, there is potential for an all-English final in Bilbao, with a coveted Champions League spot on offer for the victor.
In the Europa Conference League, Chelsea have been drawn against Danish side FC Copenhagen in the last-16.
The first legs of the last-16 ties are set to take place on Thursday, 6 March, with the return fixtures scheduled for 13 March.
Chelsea will travel to Denmark for the first leg before hosting Copenhagen at Stamford Bridge a week later.